Ěntidote: N-acetyl cysteine is a specific antidote and is most effective if used within 8 hours.Ĝardiac arrhythmias, hemorrhagic pancreatitis, disseminated intravascular coagulation.In general the recommended maximum daily dose for healthy adults is 4 grams. Ěfter 2 to 4 days: there is vomiting, jaundice, hepatic pain, bleeding, hypoglycemia, confusion, coma, metabolic acidosis and coarse flapping tremors of hands The toxic dose of paracetamol is highly variable.Ěfter 1 to 2 days: the discomfort disappears.In few hrs: patient has anorexia, nausea, vomiting, diaphoresis, hypotension, tachycardia and dyspnoea.Due to overdose, NABP accumulates and causes centrilobular liver necrosis. A small part is converted by the liver enzyme into N-acetyl-p-benzoquinoneimine. For additional information visit Linking to and Using Content from MedlinePlus.Route : Ingestion Fatal Dose : 10 to 20 gms Fatal Period : 2 to 4 days Mechanism of action : It is absorbed rapidly fro the GIT and metabolized in the liver. Any duplication or distribution of the information contained herein is strictly prohibited without authorization. To count the first dose of NAC given p.o., you have to multiply the patients weight in kg (kilograms) by 140 mg. Links to other sites are provided for information only - they do not constitute endorsements of those other sites. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. ingestion, can be prevented by prompt treatment with antidote. DOSE OF PARACETAMOL Therapeutic dose is 10-15 mg/kg Toxic dose: MECHANISM OF TOXICITY When the dose of paracetamol is high The glucuronide and sulfate. This site complies with the HONcode standard for trustworthy health information: verify here. few adverse effects when used at the recommended dose. Learn more about A.D.A.M.'s editorial policy editorial process and privacy policy. is among the first to achieve this important distinction for online health information and services. follows rigorous standards of quality and accountability. It is most effective when given within eight hours of taking the paracetamol overdose. is accredited by URAC, for Health Content Provider (URAC's accreditation program is an independent audit to verify that A.D.A.M.

Paracetamol antidote dose